In today’s Solidarity Fridays episode, Joe and Kyle sit down and discuss some very scientific (read: hard to understand) articles. First, they talk about one on Salvinorin A and its interactions with a different receptor than other psychedelics (kappa opioid receptors) and what that could mean, and a related article from Wired- a first-hand account of taking salvia as part of a brain-imaging study at Johns Hopkins University. The biggest takeaway from these can be summed up in researcher Manoj Doss’s closing quote: “Not only does this tell me how little we understand psychedelics, it also tells me how little we understand how to study them.”

They then review a recent double-blind, randomized, placebo-controlled study on LSD, which showed results we expect to see, but the full details haven’t been released yet. This leads to a discussion about intergenerational trauma and researchers finding that children of Holocaust survivors often display more trauma-related behavior than their parents, commonality between people of Irish and German decent (due to shared traumatic histories), the idea of “group soul,” how the lymphatic system works within the brain to remove toxins and how this and the blood-brain barrier can be affected by a concussion, and the effects caesarian sections have both on an individual person as well as in higher concentrations of people per country. Do countries with more C-sections produce more traumatized people?

Lastly, they talk about how psychedelics opening up people’s brains and thought processes could possibly lead toward more conspiratorial thinking, which leads to discussion about QAnon, Alan Moore, a crazy story about 9/11 from Kyle, and the very idea of truth: what is your personal criteria for something being true? What do any of us really know?

And one last reminder- October 28th is the premiere of the new 15-week online course offering called An Introduction to Philosophy and Psychedelics with Lenny Gibson, so if you’re considering taking it, now is the time to sign up!

Notable Quotes

“Do we always need to seek ego death to have profound healing in psychedelic experiences? Could it be more gentle at times?” -Kyle

“There seems to be this trend in the scientific world to say, ‘ok cool, our data suggests that this model of the world and how things are working is true, therefore this model is true’ and kind of sticking to your guns on that, and I think because we finally have our tools back where we can examine the psyche after decades of prohibition, that maybe let’s not rush- like, let’s keep them hypotheses, and perhaps we can be more fluid when new hypotheses come out about the world and the mind and the brain and these things. Perhaps that’ll help us not necessarily have to live in a certain paradigm for a super long time and we can be a little bit more paradigm-fluid maybe, or model-agnostic, and just kind of shift around as new data comes to light.” -Joe

“What’s truth and how do you know what is true? ….How can you validate that that is true? And what do you know to be true in your world? It’s a hard thing to really understand. When I think about it, I think the only true thing that I know is this present moment.” -Kyle

“It’s interesting. How do we know more? How does knowledge work? Epistemology, metaphysics-  these are massive questions, and as much as I appreciate science, I feel like science could benefit a lot from being philosophy-aware. Like, what are we really doing? What kind of metaphysics and epistemology underlies our go-forward here? Is there data to suggest that mind and brain aren’t the same thing? Yes, there is, including [from] top neurologists like Karl Pribram and others. Mind does not equal brain. And how do we transcend that and go forward? I know this is not what the establishment wants us to be saying, if we want to talk about conspiracies. Just look at scientism vs. philosophy and the humanist traditions- really, quite a battle that’s been going on for a long time, probably since the time of Newton or before.” -Joe 

Links

The Physicist and the Philosopher: Einstein, Bergson, and the Debate that Changed Our Understanding of Time, by Jimena Canales

Wired.com: This Is My Brain on Salvia

Nature.com: The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain

Psychedelics Today: Does Salvia Divinorum Have Therapeutic Potential? By Michelle Janikian

Nature.com: Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects

Psychedelicreview.com: Ketanserin info

Statista.com: Cesarean sections – Statistics & Facts

Different Doorway: Adventures of a Caesarean Born, by Jane B. English

The Concussion Repair Manual : A Practical Guide to Recovering from Traumatic Brain Injuries, by Dan Engle

Nih.gov: Brain cleaning system uses lymphatic vessels

Resonancescience.org (Resonance Science Foundation)

Nytimes.com: Cleve Backster: He talked to plants. And they talked back.

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